Dissertation: Jamison 2008

Jamison, Andrea (1/08) Primary and complex PTSD symptoms as mediators between trauma history and schizophrenia symptomatology (Paul Ramirez, Ph.D.; David Castro Blanco, Ph.D.; Joan Duncan, Ph.D.; Lewis Opler, Ph.D.)

Among individuals with schizophrenia (SCZ), rates of trauma exposure are elevated and associated with a worsened course of illness. Research has also demonstrated that posttraumatic stress disorder (PTSD) is one possible consequence of trauma that is overlooked in the SCZ population. The current study tested a theoretical model that suggested that the harmful effects of trauma history on SCZ symptoms are mediated by PTSD symptoms. Psychiatric inpatients (n = 89) were interviewed regarding their trauma history, primary and complex PTSD symptoms, and SCZ symptoms. Contrary to previous research, history of exposure to trauma was not directly related to more severe SCZ symptoms. However, SCZ symptoms were indirectly affected by trauma history's relationship to PTSD symptoms; that is to say, trauma history was related to PTSD symptoms, and PTSD symptoms were related to SCZ symptoms. These relationships lend partial support to the theoretical model's assertion that PTSD symptoms are mediators, in that any effect trauma history had on SCZ symptoms was partially explained by PTSD symptoms. These results highlight the importance of trauma assessment in a seriously mentally ill population and they suggest that future studies should look to other factors which may contribute to the worsened clinical course of SCZ patients with trauma histories.